Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine

Historical observation

20182026

Universe›Health Care›Biotechnology›Biotechnology

1 · Sector

Weight and 12M allocation change

Information Technology17.1%+1.04 pp Utilities3.4%+0.20 pp Real Estate3.4%+0.14 pp Materials2.1%-0.03 pp Consumer Discretionary7.0%-0.06 pp Energy4.6%-0.08 pp Communication Services3.4%-0.08 pp Health Care16.6%-0.13 pp Consumer Staples9.1%-0.27 pp Financials18.1%-0.33 pp Industrials15.2%-0.39 pp

2 · Industry

Inside Health Care

Biotechnology3.20%-0.18 pp Pharmaceuticals5.60%+0.10 pp Health Care Equipment2.92%+0.10 pp Health Care Services0.63%-0.07 pp Managed Health Care1.90%-0.06 pp Health Care Distributors0.47%-0.04 pp Life Sciences Tools & Services1.53%+0.02 pp Health Care Facilities0.21%+0.00 pp Health Care Supplies0.14%+0.00 pp Health Care Technology0.00%+0.00 pp

3 · Sub-industry

Inside Biotechnology

Biotechnology3.20%-0.184 pp

Concentrated

Most of this industry's losses came from a few companies.

View all contributions →

Biotechnology · weight

3.20%

Industry change · 12M

-0.18 pp

Biotechnology · contribution

-0.184 pp

Company participation

29%

of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Mar 2018 · sorted by absolute contribution to 12-month change

Company	Country	Market cap	Universe weight	3M contribution	12M contribution	12M price return	Above 6M weight average
AbbVie → ABBV	United States	$150.3bn	0.922%	-0.100 pp	-0.100 pp	-15.7%	No
Biogen → BIIB	United States	$57.9bn	0.355%	-0.064 pp	-0.064 pp	-21.3%	No
Gilead Sciences → GILD	United States	$98.8bn	0.606%	-0.018 pp	-0.018 pp	-9.4%	No
Amgen → AMGN	United States	$122.8bn	0.754%	-0.017 pp	-0.017 pp	-7.7%	No
Vertex Pharmaceuticals → VRTX	United States	$41.4bn	0.254%	+0.013 pp	+0.013 pp	-2.3%	Yes
Regeneron Pharmaceuticals → REGN	United States	$32.4bn	0.199%	+0.002 pp	+0.002 pp	-6.1%	Yes
Incyte → INCY	United States	$17.6bn	0.108%	-0.000 pp	-0.000 pp	-7.7%	No

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.