Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine

Historical observation

20182026

Universe›Health Care›Biotechnology›Biotechnology

1 · Sector

Weight and 12M allocation change

Information Technology17.6%+1.59 pp Energy5.1%+0.44 pp Utilities3.3%+0.18 pp Real Estate3.4%+0.15 pp Consumer Discretionary7.1%+0.03 pp Materials2.1%-0.02 pp Health Care16.6%-0.10 pp Communication Services3.2%-0.30 pp Industrials15.2%-0.43 pp Financials18.0%-0.50 pp Consumer Staples8.4%-1.02 pp

2 · Industry

Inside Health Care

Biotechnology3.08%-0.30 pp Health Care Equipment3.07%+0.24 pp Managed Health Care2.06%+0.10 pp Pharmaceuticals5.41%-0.09 pp Health Care Distributors0.43%-0.08 pp Health Care Services0.65%-0.06 pp Health Care Supplies0.18%+0.04 pp Life Sciences Tools & Services1.54%+0.03 pp Health Care Facilities0.22%+0.01 pp Health Care Technology0.00%+0.00 pp

3 · Sub-industry

Inside Biotechnology

Biotechnology3.08%-0.303 pp

Broad

The loss is shared across much of the industry.

View all contributions →

Biotechnology · weight

3.08%

Industry change · 12M

-0.30 pp

Biotechnology · contribution

-0.303 pp

Company participation

14%

of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

May 2018 · sorted by absolute contribution to 12-month change

Company	Country	Market cap	Universe weight	3M contribution	12M contribution	12M price return	Above 6M weight average
Gilead Sciences → GILD	United States	$87.6bn	0.532%	-0.086 pp	-0.093 pp	-19.0%	No
AbbVie → ABBV	United States	$157.0bn	0.953%	-0.150 pp	-0.069 pp	-10.9%	No
Amgen → AMGN	United States	$118.9bn	0.721%	-0.072 pp	-0.049 pp	-2.0%	No
Biogen → BIIB	United States	$62.0bn	0.376%	+0.010 pp	-0.043 pp	-15.5%	Yes
Regeneron Pharmaceuticals → REGN	United States	$28.2bn	0.171%	-0.009 pp	-0.025 pp	-18.1%	No
Incyte → INCY	United States	$14.5bn	0.088%	-0.020 pp	-0.021 pp	-24.4%	No
Vertex Pharmaceuticals → VRTX	United States	$39.2bn	0.238%	-0.015 pp	-0.003 pp	-7.7%	No

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.