Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine

Historical observation

20182026

Universe›Health Care›Biotechnology›Biotechnology

1 · Sector

Weight and 12M allocation change

Consumer Discretionary48.1%+41.00 pp Materials1.1%-1.04 pp Utilities1.9%-1.28 pp Real Estate1.8%-1.40 pp Communication Services1.9%-1.53 pp Energy2.7%-2.04 pp Consumer Staples4.8%-4.56 pp Information Technology10.0%-6.01 pp Health Care10.1%-6.67 pp Industrials8.1%-7.53 pp Financials9.5%-8.94 pp

2 · Industry

Inside Health Care

Pharmaceuticals3.37%-2.13 pp Biotechnology1.75%-1.63 pp Health Care Equipment1.86%-0.96 pp Managed Health Care1.24%-0.72 pp Life Sciences Tools & Services0.95%-0.56 pp Health Care Services0.39%-0.32 pp Health Care Distributors0.23%-0.28 pp Health Care Facilities0.15%-0.05 pp Health Care Supplies0.11%-0.03 pp Health Care Technology0.00%+0.00 pp

3 · Sub-industry

Inside Biotechnology

Biotechnology1.75%-1.628 pp

Concentrated

Most of this industry's losses came from a few companies.

View all contributions →

Biotechnology · weight

1.75%

Industry change · 12M

-1.63 pp

Biotechnology · contribution

-1.628 pp

Company participation

of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Sep 2018 · sorted by absolute contribution to 12-month change

Company	Country	Market cap	Universe weight	3M contribution	12M contribution	12M price return	Above 6M weight average
AbbVie → ABBV	United States	$143.2bn	0.456%	-0.436 pp	-0.566 pp	-14.0%	No
Amgen → AMGN	United States	$134.2bn	0.427%	-0.314 pp	-0.343 pp	+13.9%	No
Gilead Sciences → GILD	United States	$100.1bn	0.319%	-0.240 pp	-0.305 pp	-5.7%	No
Biogen → BIIB	United States	$71.2bn	0.227%	-0.145 pp	-0.193 pp	+1.6%	No
Vertex Pharmaceuticals → VRTX	United States	$49.3bn	0.157%	-0.106 pp	-0.084 pp	+15.5%	No
Regeneron Pharmaceuticals → REGN	United States	$38.0bn	0.121%	-0.076 pp	-0.076 pp	+10.2%	No
Incyte → INCY	United States	$14.7bn	0.047%	-0.039 pp	-0.062 pp	-23.5%	No

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.