Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine

Historical observation

20182026

Universe›Health Care›Biotechnology›Biotechnology

1 · Sector

Weight and 12M allocation change

Consumer Discretionary48.2%+41.13 pp Materials1.1%-1.05 pp Utilities2.0%-1.12 pp Real Estate2.0%-1.28 pp Communication Services2.0%-1.49 pp Energy2.5%-2.22 pp Consumer Staples5.2%-4.15 pp Information Technology9.8%-6.27 pp Health Care10.0%-6.71 pp Industrials7.6%-7.94 pp Financials9.6%-8.89 pp

2 · Industry

Inside Health Care

Pharmaceuticals3.54%-1.96 pp Biotechnology1.63%-1.76 pp Health Care Equipment1.79%-1.03 pp Managed Health Care1.29%-0.66 pp Life Sciences Tools & Services0.93%-0.58 pp Health Care Services0.38%-0.33 pp Health Care Distributors0.23%-0.28 pp Health Care Supplies0.07%-0.07 pp Health Care Facilities0.16%-0.05 pp Health Care Technology0.00%+0.00 pp

3 · Sub-industry

Inside Biotechnology

Biotechnology1.63%-1.757 pp

Concentrated

Most of this industry's losses came from a few companies.

View all contributions →

Biotechnology · weight

1.63%

Industry change · 12M

-1.76 pp

Biotechnology · contribution

-1.757 pp

Company participation

of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Oct 2018 · sorted by absolute contribution to 12-month change

Company	Country	Market cap	Universe weight	3M contribution	12M contribution	12M price return	Above 6M weight average
AbbVie → ABBV	United States	$117.9bn	0.400%	-0.454 pp	-0.622 pp	-28.4%	No
Amgen → AMGN	United States	$122.8bn	0.416%	-0.326 pp	-0.354 pp	+5.9%	No
Gilead Sciences → GILD	United States	$88.4bn	0.300%	-0.291 pp	-0.325 pp	-16.8%	No
Biogen → BIIB	United States	$61.3bn	0.208%	-0.185 pp	-0.212 pp	-12.5%	No
Vertex Pharmaceuticals → VRTX	United States	$43.3bn	0.147%	-0.114 pp	-0.094 pp	+1.6%	No
Regeneron Pharmaceuticals → REGN	United States	$31.9bn	0.108%	-0.094 pp	-0.088 pp	-7.5%	No
Incyte → INCY	United States	$13.8bn	0.047%	-0.036 pp	-0.062 pp	-28.2%	No

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.