Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine

Historical observation

20182026

Universe›Health Care›Biotechnology›Biotechnology

1 · Sector

Weight and 12M allocation change

Consumer Discretionary47.6%+40.56 pp Materials1.4%-0.73 pp Utilities2.1%-1.09 pp Real Estate2.0%-1.22 pp Communication Services2.1%-1.38 pp Energy2.4%-2.26 pp Consumer Staples5.2%-4.20 pp Health Care10.5%-6.24 pp Information Technology9.7%-6.37 pp Industrials7.4%-8.17 pp Financials9.6%-8.90 pp

2 · Industry

Inside Health Care

Pharmaceuticals3.66%-1.84 pp Biotechnology1.76%-1.62 pp Health Care Equipment1.88%-0.95 pp Managed Health Care1.35%-0.61 pp Life Sciences Tools & Services0.98%-0.53 pp Health Care Services0.39%-0.32 pp Health Care Distributors0.23%-0.28 pp Health Care Supplies0.07%-0.06 pp Health Care Facilities0.16%-0.04 pp Health Care Technology0.00%+0.00 pp

3 · Sub-industry

Inside Biotechnology

Biotechnology1.76%-1.624 pp

Concentrated

Most of this industry's losses came from a few companies.

View all contributions →

Biotechnology · weight

1.76%

Industry change · 12M

-1.62 pp

Biotechnology · contribution

-1.624 pp

Company participation

of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Nov 2018 · sorted by absolute contribution to 12-month change

Company	Country	Market cap	Universe weight	3M contribution	12M contribution	12M price return	Above 6M weight average
AbbVie → ABBV	United States	$141.8bn	0.471%	+0.002 pp	-0.551 pp	-13.3%	No
Amgen → AMGN	United States	$132.7bn	0.441%	+0.023 pp	-0.329 pp	+15.2%	No
Gilead Sciences → GILD	United States	$93.1bn	0.309%	-0.008 pp	-0.315 pp	-12.2%	No
Biogen → BIIB	United States	$67.2bn	0.223%	-0.006 pp	-0.196 pp	-4.1%	No
Vertex Pharmaceuticals → VRTX	United States	$46.2bn	0.153%	+0.001 pp	-0.087 pp	+8.3%	No
Regeneron Pharmaceuticals → REGN	United States	$34.4bn	0.114%	-0.009 pp	-0.082 pp	-0.3%	No
Incyte → INCY	United States	$13.7bn	0.045%	-0.005 pp	-0.063 pp	-28.8%	No

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.