Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine

Historical observation

20182026

Universe›Health Care›Biotechnology›Biotechnology

1 · Sector

Weight and 12M allocation change

Consumer Discretionary48.7%+41.63 pp Materials1.4%-0.72 pp Utilities2.1%-1.03 pp Real Estate2.0%-1.23 pp Communication Services2.0%-1.42 pp Energy2.4%-2.32 pp Consumer Staples5.1%-4.27 pp Health Care10.4%-6.37 pp Information Technology9.5%-6.56 pp Industrials7.2%-8.34 pp Financials9.1%-9.36 pp

2 · Industry

Inside Health Care

Pharmaceuticals3.66%-1.84 pp Biotechnology1.77%-1.61 pp Health Care Equipment1.89%-0.94 pp Managed Health Care1.28%-0.67 pp Life Sciences Tools & Services0.97%-0.54 pp Health Care Services0.35%-0.36 pp Health Care Distributors0.21%-0.29 pp Health Care Supplies0.07%-0.07 pp Health Care Facilities0.15%-0.05 pp Health Care Technology0.00%+0.00 pp

3 · Sub-industry

Inside Biotechnology

Biotechnology1.77%-1.611 pp

Concentrated

Most of this industry's losses came from a few companies.

View all contributions →

Biotechnology · weight

1.77%

Industry change · 12M

-1.61 pp

Biotechnology · contribution

-1.611 pp

Company participation

of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Dec 2018 · sorted by absolute contribution to 12-month change

Company	Country	Market cap	Universe weight	3M contribution	12M contribution	12M price return	Above 6M weight average
AbbVie → ABBV	United States	$138.7bn	0.496%	+0.039 pp	-0.526 pp	-15.3%	No
Gilead Sciences → GILD	United States	$80.9bn	0.289%	-0.030 pp	-0.335 pp	-23.0%	No
Amgen → AMGN	United States	$124.0bn	0.443%	+0.016 pp	-0.327 pp	+7.7%	No
Biogen → BIIB	United States	$60.6bn	0.217%	-0.010 pp	-0.203 pp	-13.5%	No
Vertex Pharmaceuticals → VRTX	United States	$42.3bn	0.151%	-0.006 pp	-0.089 pp	-0.7%	No
Regeneron Pharmaceuticals → REGN	United States	$35.1bn	0.125%	+0.005 pp	-0.071 pp	+1.9%	No
Incyte → INCY	United States	$13.5bn	0.048%	+0.002 pp	-0.060 pp	-29.6%	No

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.