Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine

Historical observation

20182026

Universe›Health Care›Biotechnology›Biotechnology

1 · Sector

Weight and 12M allocation change

Communication Services5.0%+1.82 pp Consumer Staples9.1%+0.76 pp Materials2.8%+0.64 pp Utilities3.9%+0.57 pp Health Care17.2%+0.54 pp Real Estate3.9%+0.51 pp Consumer Discretionary7.0%-0.07 pp Information Technology17.6%-0.07 pp Energy3.9%-1.29 pp Financials16.3%-1.64 pp Industrials13.4%-1.77 pp

2 · Industry

Inside Health Care

Biotechnology2.47%-0.61 pp Pharmaceuticals5.81%+0.39 pp Life Sciences Tools & Services1.83%+0.29 pp Health Care Services0.92%+0.27 pp Health Care Equipment3.30%+0.23 pp Health Care Distributors0.36%-0.07 pp Managed Health Care2.09%+0.03 pp Health Care Supplies0.15%-0.02 pp Health Care Facilities0.24%+0.02 pp Health Care Technology0.00%+0.00 pp

3 · Sub-industry

Inside Biotechnology

Biotechnology2.47%-0.607 pp

Concentrated

Most of this industry's losses came from a few companies.

View all contributions →

Biotechnology · weight

2.47%

Industry change · 12M

-0.61 pp

Biotechnology · contribution

-0.607 pp

Company participation

71%

of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

May 2019 · sorted by absolute contribution to 12-month change

Company	Country	Market cap	Universe weight	3M contribution	12M contribution	12M price return	Above 6M weight average
AbbVie → ABBV	United States	$113.4bn	0.660%	-0.017 pp	-0.292 pp	-18.8%	Yes
Amgen → AMGN	United States	$101.7bn	0.592%	-0.093 pp	-0.129 pp	-4.4%	Yes
Biogen → BIIB	United States	$42.5bn	0.248%	-0.126 pp	-0.129 pp	-25.4%	No
Gilead Sciences → GILD	United States	$79.2bn	0.461%	-0.020 pp	-0.071 pp	-4.5%	Yes
Incyte → INCY	United States	$16.9bn	0.098%	-0.009 pp	+0.010 pp	+15.2%	Yes
Vertex Pharmaceuticals → VRTX	United States	$42.6bn	0.248%	-0.032 pp	+0.010 pp	+7.9%	Yes
Regeneron Pharmaceuticals → REGN	United States	$28.3bn	0.165%	-0.069 pp	-0.006 pp	+0.5%	No

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.