Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine

Historical observation

20182026

Universe›Health Care›Biotechnology›Biotechnology

1 · Sector

Weight and 12M allocation change

Communication Services4.9%+1.57 pp Materials2.8%+0.74 pp Utilities3.7%+0.31 pp Information Technology17.7%+0.29 pp Real Estate3.7%+0.14 pp Consumer Staples8.8%+0.03 pp Health Care16.9%-0.00 pp Consumer Discretionary7.0%-0.03 pp Industrials14.5%-0.19 pp Energy3.9%-1.21 pp Financials16.1%-1.65 pp

2 · Industry

Inside Health Care

Biotechnology2.40%-0.71 pp Life Sciences Tools & Services1.90%+0.35 pp Health Care Services0.91%+0.25 pp Health Care Equipment3.33%+0.23 pp Managed Health Care1.95%-0.16 pp Pharmaceuticals5.61%+0.11 pp Health Care Distributors0.37%-0.06 pp Health Care Supplies0.14%-0.04 pp Health Care Facilities0.25%+0.03 pp Health Care Technology0.00%+0.00 pp

3 · Sub-industry

Inside Biotechnology

Biotechnology2.40%-0.706 pp

Concentrated

Most of this industry's losses came from a few companies.

View all contributions →

Biotechnology · weight

2.40%

Industry change · 12M

-0.71 pp

Biotechnology · contribution

-0.706 pp

Company participation

57%

of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Jun 2019 · sorted by absolute contribution to 12-month change

Company	Country	Market cap	Universe weight	3M contribution	12M contribution	12M price return	Above 6M weight average
AbbVie → ABBV	United States	$107.5bn	0.580%	-0.103 pp	-0.312 pp	-17.8%	No
Amgen → AMGN	United States	$112.4bn	0.606%	-0.073 pp	-0.135 pp	+2.9%	Yes
Biogen → BIIB	United States	$45.3bn	0.244%	-0.023 pp	-0.127 pp	-19.4%	No
Gilead Sciences → GILD	United States	$85.9bn	0.463%	-0.013 pp	-0.096 pp	-1.2%	Yes
Regeneron Pharmaceuticals → REGN	United States	$29.4bn	0.159%	-0.063 pp	-0.038 pp	-9.3%	No
Incyte → INCY	United States	$18.2bn	0.098%	-0.008 pp	+0.012 pp	+26.8%	Yes
Vertex Pharmaceuticals → VRTX	United States	$47.0bn	0.253%	-0.017 pp	-0.010 pp	+7.9%	Yes

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.