Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine

Historical observation

20182026

Universe›Health Care›Biotechnology›Biotechnology

1 · Sector

Weight and 12M allocation change

Information Technology26.2%+5.17 pp Consumer Discretionary7.6%+1.03 pp Industrials12.5%+0.98 pp Financials14.5%+0.40 pp Materials3.4%+0.25 pp Energy2.2%-0.33 pp Utilities3.2%-0.52 pp Real Estate3.1%-0.54 pp Communication Services4.6%-0.59 pp Consumer Staples7.1%-2.07 pp Health Care15.5%-3.78 pp

2 · Industry

Inside Health Care

Pharmaceuticals4.48%-1.87 pp Biotechnology2.08%-1.01 pp Managed Health Care2.04%-0.41 pp Health Care Equipment3.24%-0.35 pp Health Care Services0.87%-0.20 pp Health Care Supplies0.28%+0.16 pp Life Sciences Tools & Services1.94%-0.07 pp Health Care Distributors0.30%-0.07 pp Health Care Facilities0.24%+0.03 pp Health Care Technology0.00%+0.00 pp

3 · Sub-industry

Inside Biotechnology

Biotechnology2.08%-1.011 pp

Concentrated

Most of this industry's losses came from a few companies.

View all contributions →

Biotechnology · weight

2.08%

Industry change · 12M

-1.01 pp

Biotechnology · contribution

-1.011 pp

Company participation

100%

of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Apr 2021 · sorted by absolute contribution to 12-month change

Company	Country	Market cap	Universe weight	3M contribution	12M contribution	12M price return	Above 6M weight average
Gilead Sciences → GILD	United States	$79.8bn	0.289%	+0.092 pp	-0.305 pp	-21.2%	Yes
Amgen → AMGN	United States	$137.7bn	0.499%	+0.162 pp	-0.291 pp	+3.0%	Yes
Vertex Pharmaceuticals → VRTX	United States	$56.5bn	0.205%	+0.062 pp	-0.160 pp	-13.1%	Yes
Biogen → BIIB	United States	$40.2bn	0.146%	+0.042 pp	-0.125 pp	-9.9%	Yes
Regeneron Pharmaceuticals → REGN	United States	$45.2bn	0.164%	+0.051 pp	-0.113 pp	-8.5%	Yes
Incyte → INCY	United States	$18.8bn	0.068%	+0.021 pp	-0.050 pp	-12.6%	Yes
AbbVie → ABBV	United States	$196.9bn	0.714%	+0.280 pp	+0.033 pp	+42.5%	Yes

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.