Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine
Historical observation
20182026
Universe›Health Care›Biotechnology›Biotechnology
Biotechnology · weight
2.50%
Industry change · 12M
+0.42 pp
Biotechnology · contribution
+0.416 pp
Company participation
63%
of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Apr 2022 · sorted by absolute contribution to 12-month change

CompanyCountryMarket capUniverse weight3M contribution12M contribution12M price returnAbove 6M weight average
AbbVie →
ABBV
United States$259.8bn0.939%+0.125 pp+0.226 pp+37.4%Yes
Moderna →
MRNA
United States$54.2bn0.196%-0.035 pp+0.196 pp-24.8%No
Regeneron Pharmaceuticals →
REGN
United States$61.9bn0.224%+0.032 pp+0.060 pp+36.9%Yes
Amgen →
AMGN
United States$124.6bn0.450%+0.020 pp-0.049 pp+0.4%Yes
Vertex Pharmaceuticals →
VRTX
United States$69.6bn0.251%+0.044 pp+0.047 pp+25.2%Yes
Biogen →
BIIB
United States$30.5bn0.110%-0.001 pp-0.036 pp-22.4%No
Gilead Sciences →
GILD
United States$74.4bn0.269%-0.021 pp-0.020 pp-2.4%No
Incyte →
INCY
United States$16.6bn0.060%+0.005 pp-0.008 pp-12.2%Yes

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.