Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine
Historical observation
20182026
Universe›Health Care›Biotechnology›Biotechnology
Biotechnology · weight
2.57%
Industry change · 12M
+0.50 pp
Biotechnology · contribution
+0.495 pp
Company participation
75%
of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

May 2022 · sorted by absolute contribution to 12-month change

CompanyCountryMarket capUniverse weight3M contribution12M contribution12M price returnAbove 6M weight average
AbbVie →
ABBV
United States$260.4bn0.938%+0.031 pp+0.222 pp+35.8%Yes
Moderna →
MRNA
United States$57.8bn0.208%-0.006 pp+0.208 pp-21.4%No
Regeneron Pharmaceuticals →
REGN
United States$62.5bn0.225%+0.023 pp+0.056 pp+32.3%Yes
Vertex Pharmaceuticals →
VRTX
United States$68.7bn0.247%+0.044 pp+0.054 pp+28.8%Yes
Biogen →
BIIB
United States$29.3bn0.105%-0.002 pp-0.039 pp-25.2%No
Incyte →
INCY
United States$16.8bn0.061%+0.008 pp-0.005 pp-9.4%Yes
Amgen →
AMGN
United States$137.2bn0.494%+0.056 pp+0.004 pp+11.5%Yes
Gilead Sciences →
GILD
United States$81.3bn0.293%+0.030 pp-0.004 pp+2.4%Yes

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.