Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine
Historical observation
20182026
Universe›Health Care›Biotechnology›Biotechnology
Biotechnology · weight
2.65%
Industry change · 12M
+0.14 pp
Biotechnology · contribution
+0.136 pp
Company participation
75%
of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Sep 2022 · sorted by absolute contribution to 12-month change

CompanyCountryMarket capUniverse weight3M contribution12M contribution12M price returnAbove 6M weight average
Moderna →
MRNA
United States$46.3bn0.182%-0.039 pp-0.364 pp-69.3%No
AbbVie →
ABBV
United States$237.3bn0.933%-0.120 pp+0.263 pp+29.5%Yes
Vertex Pharmaceuticals →
VRTX
United States$74.3bn0.292%+0.012 pp+0.127 pp+59.6%Yes
Regeneron Pharmaceuticals →
REGN
United States$64.7bn0.254%+0.038 pp+0.055 pp+13.8%Yes
Amgen →
AMGN
United States$120.6bn0.474%-0.032 pp+0.050 pp+9.5%Yes
Incyte →
INCY
United States$14.8bn0.058%-0.007 pp+0.005 pp-3.1%No
Biogen →
BIIB
United States$38.7bn0.152%+0.036 pp+0.004 pp-5.7%Yes
Gilead Sciences →
GILD
United States$77.3bn0.304%+0.002 pp-0.004 pp-7.5%Yes

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.