Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine
Historical observation
20182026
Universe›Health Care›Biotechnology›Biotechnology
Biotechnology · weight
2.90%
Industry change · 12M
+0.57 pp
Biotechnology · contribution
+0.567 pp
Company participation
88%
of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Dec 2022 · sorted by absolute contribution to 12-month change

CompanyCountryMarket capUniverse weight3M contribution12M contribution12M price returnAbove 6M weight average
AbbVie →
ABBV
United States$285.8bn1.031%+0.099 pp+0.265 pp+24.0%Yes
Amgen →
AMGN
United States$140.1bn0.506%+0.032 pp+0.100 pp+20.4%Yes
Gilead Sciences →
GILD
United States$107.7bn0.389%+0.085 pp+0.097 pp+23.6%Yes
Vertex Pharmaceuticals →
VRTX
United States$74.1bn0.267%-0.024 pp+0.089 pp+31.5%No
Moderna →
MRNA
United States$69.0bn0.249%+0.067 pp-0.081 pp-29.3%Yes
Regeneron Pharmaceuticals →
REGN
United States$67.8bn0.245%-0.010 pp+0.055 pp+14.2%Yes
Biogen →
BIIB
United States$39.9bn0.144%-0.008 pp+0.031 pp+15.4%Yes
Incyte →
INCY
United States$17.9bn0.064%+0.006 pp+0.013 pp+9.4%Yes

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.