Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine
Historical observation
20182026
Universe›Health Care›Biotechnology›Biotechnology
Biotechnology · weight
2.61%
Industry change · 12M
+0.11 pp
Biotechnology · contribution
+0.110 pp
Company participation
38%
of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Apr 2023 · sorted by absolute contribution to 12-month change

CompanyCountryMarket capUniverse weight3M contribution12M contribution12M price returnAbove 6M weight average
Gilead Sciences →
GILD
United States$102.5bn0.346%-0.014 pp+0.077 pp+44.4%No
Vertex Pharmaceuticals →
VRTX
United States$87.6bn0.296%+0.012 pp+0.044 pp+24.7%Yes
Biogen →
BIIB
United States$44.0bn0.149%+0.005 pp+0.038 pp+46.7%Yes
AbbVie →
ABBV
United States$267.4bn0.903%+0.009 pp-0.036 pp+6.9%No
Regeneron Pharmaceuticals →
REGN
United States$75.3bn0.254%+0.011 pp+0.031 pp+21.6%Yes
Moderna →
MRNA
United States$51.3bn0.173%-0.058 pp-0.022 pp-1.1%No
Amgen →
AMGN
United States$128.1bn0.433%-0.028 pp-0.018 pp+6.1%No
Incyte →
INCY
United States$16.6bn0.056%-0.009 pp-0.004 pp-0.7%No

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.