Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine
Historical observation
20182026
Universe›Health Care›Biotechnology›Biotechnology
Biotechnology · weight
2.47%
Industry change · 12M
-0.26 pp
Biotechnology · contribution
-0.259 pp
Company participation
88%
of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Oct 2023 · sorted by absolute contribution to 12-month change

CompanyCountryMarket capUniverse weight3M contribution12M contribution12M price returnAbove 6M weight average
Moderna →
MRNA
United States$28.9bn0.098%+0.001 pp-0.110 pp-49.5%No
AbbVie →
ABBV
United States$249.2bn0.847%+0.272 pp-0.071 pp+0.3%Yes
Amgen →
AMGN
United States$136.8bn0.465%+0.193 pp-0.048 pp-2.2%Yes
Vertex Pharmaceuticals →
VRTX
United States$93.5bn0.318%+0.120 pp+0.034 pp+16.1%Yes
Biogen →
BIIB
United States$34.4bn0.117%+0.032 pp-0.028 pp-16.2%Yes
Incyte →
INCY
United States$12.1bn0.041%+0.010 pp-0.018 pp-27.5%Yes
Gilead Sciences →
GILD
United States$97.9bn0.333%+0.126 pp-0.016 pp+3.9%Yes
Regeneron Pharmaceuticals →
REGN
United States$73.3bn0.249%+0.097 pp-0.001 pp+4.2%Yes

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.