Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine

Historical observation

20182026

Universe›Health Care›Biotechnology›Biotechnology

1 · Sector

Weight and 12M allocation change

Information Technology34.8%+5.79 pp Financials11.4%+0.39 pp Utilities2.9%-0.05 pp Industrials9.8%-0.10 pp Consumer Staples7.0%-0.16 pp Real Estate2.6%-0.19 pp Materials2.5%-0.37 pp Communication Services2.5%-0.40 pp Consumer Discretionary11.2%-0.92 pp Energy2.5%-1.08 pp Health Care12.9%-2.90 pp

2 · Industry

Inside Health Care

Pharmaceuticals4.23%-0.88 pp Managed Health Care1.59%-0.80 pp Biotechnology2.13%-0.34 pp Life Sciences Tools & Services1.24%-0.28 pp Health Care Equipment2.52%-0.27 pp Health Care Services0.49%-0.26 pp Health Care Distributors0.34%-0.10 pp Health Care Technology0.03%+0.03 pp Health Care Facilities0.21%+0.01 pp Health Care Supplies0.14%-0.00 pp

3 · Sub-industry

Inside Biotechnology

Biotechnology2.13%-0.341 pp

Broad

The loss is shared across much of the industry.

View all contributions →

Biotechnology · weight

2.13%

Industry change · 12M

-0.34 pp

Biotechnology · contribution

-0.341 pp

Company participation

63%

of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Oct 2024 · sorted by absolute contribution to 12-month change

Company	Country	Market cap	Universe weight	3M contribution	12M contribution	12M price return	Above 6M weight average
Gilead Sciences → GILD	United States	$110.6bn	0.260%	+0.090 pp	-0.073 pp	+17.8%	Yes
Regeneron Pharmaceuticals → REGN	United States	$78.8bn	0.185%	+0.003 pp	-0.064 pp	+7.5%	No
Amgen → AMGN	United States	$172.1bn	0.404%	+0.085 pp	-0.061 pp	+29.0%	Yes
Biogen → BIIB	United States	$25.4bn	0.060%	+0.004 pp	-0.057 pp	-26.7%	No
Moderna → MRNA	United States	$20.9bn	0.049%	-0.033 pp	-0.049 pp	-28.4%	No
Vertex Pharmaceuticals → VRTX	United States	$122.9bn	0.289%	+0.059 pp	-0.029 pp	+31.4%	Yes
Incyte → INCY	United States	$14.3bn	0.034%	+0.011 pp	-0.008 pp	+37.4%	Yes
AbbVie → ABBV	United States	$360.1bn	0.846%	+0.260 pp	-0.001 pp	+49.7%	Yes

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.