Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine
Historical observation
20182026
Universe›Health Care›Biotechnology›Biotechnology
Biotechnology · weight
1.86%
Industry change · 12M
+0.26 pp
Biotechnology · contribution
+0.259 pp
Company participation
13%
of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

May 2025 · sorted by absolute contribution to 12-month change

CompanyCountryMarket capUniverse weight3M contribution12M contribution12M price returnAbove 6M weight average
AbbVie →
ABBV
United States$328.7bn0.745%-0.080 pp+0.201 pp+19.6%No
Gilead Sciences →
GILD
United States$136.9bn0.310%-0.008 pp+0.157 pp+77.7%Yes
Moderna →
MRNA
United States$10.3bn0.023%-0.003 pp-0.081 pp-81.4%No
Regeneron Pharmaceuticals →
REGN
United States$46.1bn0.104%-0.042 pp-0.072 pp-49.8%No
Amgen →
AMGN
United States$155.0bn0.351%-0.019 pp+0.037 pp-2.7%No
Vertex Pharmaceuticals →
VRTX
United States$113.5bn0.257%-0.018 pp+0.033 pp-2.9%No
Biogen →
BIIB
United States$19.0bn0.043%-0.003 pp-0.020 pp-42.3%No
Incyte →
INCY
United States$12.6bn0.029%-0.003 pp+0.004 pp+12.6%No

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.