Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine
Historical observation
20182026
Universe›Health Care›Biotechnology›Biotechnology

1 · Sector

Weight and 12M allocation change

Information Technology37.8%+2.39 ppIndustrials9.6%+0.25 ppMaterials2.2%+0.06 ppUtilities2.6%-0.01 ppFinancials11.9%-0.11 ppEnergy2.3%-0.17 ppReal Estate2.1%-0.28 ppCommunication Services2.2%-0.31 ppHealth Care11.3%-0.33 ppConsumer Staples6.0%-0.70 ppConsumer Discretionary12.0%-0.78 pp

2 · Industry

Inside Health Care

Managed Health Care0.84%-0.55 ppPharmaceuticals4.11%+0.28 ppHealth Care Equipment2.25%-0.18 ppLife Sciences Tools & Services1.03%-0.12 ppBiotechnology1.91%+0.12 ppHealth Care Distributors0.44%+0.09 ppHealth Care Supplies0.09%-0.04 ppHealth Care Facilities0.21%+0.04 ppHealth Care Services0.44%+0.02 ppHealth Care Technology0.03%+0.00 pp

3 · Sub-industry

Inside Biotechnology

Biotechnology1.91%+0.118 pp
Concentrated

Most of this industry's gains came from a few companies.

View all contributions →
Biotechnology · weight
1.91%
Industry change · 12M
+0.12 pp
Biotechnology · contribution
+0.118 pp
Company participation
100%
of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Dec 2025 · sorted by absolute contribution to 12-month change

CompanyCountryMarket capUniverse weight3M contribution12M contribution12M price returnAbove 6M weight average
AbbVie →
ABBV
United States$403.8bn0.791%-0.028 pp+0.079 pp+33.1%Yes
Gilead Sciences →
GILD
United States$152.3bn0.298%+0.023 pp+0.037 pp+36.6%Yes
Amgen →
AMGN
United States$176.3bn0.345%+0.041 pp+0.028 pp+29.7%Yes
Moderna →
MRNA
United States$11.5bn0.023%+0.002 pp-0.014 pp-29.1%Yes
Vertex Pharmaceuticals →
VRTX
United States$115.0bn0.225%+0.024 pp-0.010 pp+12.6%Yes
Regeneron Pharmaceuticals →
REGN
United States$72.5bn0.142%+0.036 pp-0.010 pp+9.0%Yes
Incyte →
INCY
United States$19.4bn0.038%+0.005 pp+0.008 pp+43.0%Yes
Biogen →
BIIB
United States$25.8bn0.051%+0.009 pp+0.000 pp+15.1%Yes

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.