Observatory · observe first
Follow the allocation change
Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.
Historical time machine
Historical observation
20182026
1 · Sector
Weight and 12M allocation change
2 · Industry
Inside Health Care
Managed Health Care0.73%-0.73 ppHealth Care Equipment2.13%-0.49 ppLife Sciences Tools & Services0.99%-0.21 ppPharmaceuticals4.08%+0.20 ppHealth Care Distributors0.44%+0.08 ppBiotechnology1.93%+0.08 ppHealth Care Supplies0.08%-0.05 ppHealth Care Services0.42%-0.04 ppHealth Care Facilities0.21%+0.03 ppHealth Care Technology0.03%-0.00 pp
3 · Sub-industry
Inside Biotechnology
Biotechnology · weight
1.93%
Industry change · 12M
+0.08 pp
Biotechnology · contribution
+0.076 pp
Company participation
88%
of industry constituents above their 6M weight average
4 · Companies driving this sub-industry
Jan 2026 · sorted by absolute contribution to 12-month change
| Company | Country | Market cap | Universe weight | 3M contribution | 12M contribution | 12M price return | Above 6M weight average |
|---|---|---|---|---|---|---|---|
| Gilead Sciences → GILD | United States | $176.1bn | 0.337% | +0.046 pp | +0.068 pp | +50.1% | Yes |
| Vertex Pharmaceuticals → VRTX | United States | $119.2bn | 0.228% | +0.014 pp | -0.036 pp | +1.8% | Yes |
| AbbVie → ABBV | United States | $394.1bn | 0.754% | -0.000 pp | +0.032 pp | +25.3% | No |
| Amgen → AMGN | United States | $184.1bn | 0.352% | +0.037 pp | +0.011 pp | +23.7% | Yes |
| Regeneron Pharmaceuticals → REGN | United States | $69.7bn | 0.133% | +0.013 pp | -0.007 pp | +10.8% | Yes |
| Incyte → INCY | United States | $19.6bn | 0.038% | +0.002 pp | +0.006 pp | +34.9% | Yes |
| Biogen → BIIB | United States | $26.4bn | 0.050% | +0.006 pp | +0.004 pp | +25.0% | Yes |
| Moderna → MRNA | United States | $17.2bn | 0.033% | +0.012 pp | -0.001 pp | +11.8% | Yes |
Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.