Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine
Historical observation
20182026
Universe›Health Care›Biotechnology›Biotechnology
Biotechnology · weight
1.45%
Industry change · 12M
-0.69 pp
Biotechnology · contribution
-0.690 pp
Company participation
13%
of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Mar 2026 · sorted by absolute contribution to 12-month change

CompanyCountryMarket capUniverse weight3M contribution12M contribution12M price returnAbove 6M weight average
AbbVie →
ABBV
United States$384.6bn0.560%-0.231 pp-0.318 pp+7.3%No
Vertex Pharmaceuticals →
VRTX
United States$113.4bn0.165%-0.060 pp-0.130 pp-7.9%No
Amgen →
AMGN
United States$189.7bn0.276%-0.069 pp-0.121 pp+16.5%No
Gilead Sciences →
GILD
United States$173.0bn0.252%-0.046 pp-0.079 pp+27.7%No
Regeneron Pharmaceuticals →
REGN
United States$72.6bn0.106%-0.036 pp-0.036 pp+22.5%No
Biogen →
BIIB
United States$26.9bn0.039%-0.011 pp-0.008 pp+34.0%No
Moderna →
MRNA
United States$20.1bn0.029%+0.007 pp+0.003 pp+79.2%Yes
Incyte →
INCY
United States$18.7bn0.027%-0.011 pp-0.001 pp+55.4%No

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.