Observatory · observe first
Follow the allocation change
Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.
Historical time machine
Historical observation
20182026
1 · Sector
Weight and 12M allocation change
2 · Industry
Inside Health Care
Health Care Equipment1.51%-1.12 ppPharmaceuticals3.80%+0.22 ppBiotechnology1.68%-0.18 ppLife Sciences Tools & Services0.80%-0.12 ppHealth Care Distributors0.34%-0.09 ppManaged Health Care0.86%-0.08 ppHealth Care Services0.42%-0.07 ppHealth Care Facilities0.15%-0.06 ppHealth Care Technology0.07%+0.04 ppHealth Care Supplies0.08%-0.01 pp
3 · Sub-industry
Inside Biotechnology
Biotechnology · weight
1.68%
Industry change · 12M
-0.18 pp
Biotechnology · contribution
-0.179 pp
Company participation
88%
of industry constituents above their 6M weight average
4 · Companies driving this sub-industry
May 2026 · sorted by absolute contribution to 12-month change
| Company | Country | Market cap | Universe weight | 3M contribution | 12M contribution | 12M price return | Above 6M weight average |
|---|---|---|---|---|---|---|---|
| AbbVie → ABBV | United States | $384.7bn | 0.667% | +0.103 pp | -0.078 pp | +20.8% | Yes |
| Vertex Pharmaceuticals → VRTX | United States | $113.6bn | 0.197% | +0.024 pp | -0.060 pp | +1.2% | Yes |
| Amgen → AMGN | United States | $181.8bn | 0.315% | +0.028 pp | -0.036 pp | +20.4% | Yes |
| Gilead Sciences → GILD | United States | $166.9bn | 0.289% | +0.035 pp | -0.021 pp | +25.4% | Yes |
| Moderna → MRNA | United States | $18.7bn | 0.032% | +0.003 pp | +0.009 pp | +77.7% | Yes |
| Biogen → BIIB | United States | $28.9bn | 0.050% | +0.012 pp | +0.007 pp | +51.0% | Yes |
| Incyte → INCY | United States | $19.3bn | 0.033% | +0.006 pp | +0.005 pp | +48.7% | Yes |
| Regeneron Pharmaceuticals → REGN | United States | $57.8bn | 0.100% | -0.001 pp | -0.004 pp | +26.1% | No |
Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.