Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine
Historical observation
20182026
Universe›Health Care›Biotechnology›Biotechnology

1 · Sector

Weight and 12M allocation change

Information Technology40.9%+4.04 ppEnergy3.9%+1.55 ppHealth Care10.6%+0.01 ppCommunication Services2.3%-0.19 ppMaterials2.0%-0.23 ppReal Estate1.9%-0.31 ppIndustrials9.3%-0.48 ppUtilities2.2%-0.48 ppConsumer Staples5.5%-0.92 ppConsumer Discretionary10.8%-1.27 ppFinancials10.5%-1.72 pp

2 · Industry

Inside Health Care

Health Care Equipment1.61%-0.81 ppPharmaceuticals4.07%+0.65 ppBiotechnology1.99%+0.19 ppHealth Care Technology0.10%+0.08 ppHealth Care Facilities0.15%-0.04 ppHealth Care Services0.43%-0.04 ppLife Sciences Tools & Services0.93%-0.03 ppManaged Health Care0.85%+0.02 ppHealth Care Supplies0.08%-0.00 ppHealth Care Distributors0.38%-0.00 pp

3 · Sub-industry

Inside Biotechnology

Biotechnology1.99%+0.189 pp
Concentrated

Most of this industry's gains came from a few companies.

View all contributions →
Biotechnology · weight
1.99%
Industry change · 12M
+0.19 pp
Biotechnology · contribution
+0.189 pp
Company participation
100%
of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Aug 2026 · sorted by absolute contribution to 12-month change

CompanyCountryMarket capUniverse weight3M contribution12M contribution12M price returnAbove 6M weight average
Moderna →
MRNA
United States$56.0bn0.093%+0.061 pp+0.074 pp+482.6%Yes
Amgen →
AMGN
United States$232.4bn0.387%+0.072 pp+0.066 pp+53.6%Yes
Vertex Pharmaceuticals →
VRTX
United States$138.0bn0.230%+0.033 pp+0.022 pp+39.3%Yes
AbbVie →
ABBV
United States$453.1bn0.755%+0.088 pp-0.016 pp+25.7%Yes
Biogen →
BIIB
United States$32.0bn0.053%+0.003 pp+0.013 pp+63.9%Yes
Regeneron Pharmaceuticals →
REGN
United States$75.1bn0.125%+0.025 pp+0.012 pp+38.3%Yes
Gilead Sciences →
GILD
United States$181.5bn0.302%+0.013 pp+0.012 pp+32.9%Yes
Incyte →
INCY
United States$24.6bn0.041%+0.008 pp+0.007 pp+45.6%Yes

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.