Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine
Historical observation
20182026
Universe›Health Care›Biotechnology›Biotechnology
Biotechnology · weight
2.33%
Industry change · 12M
+0.06 pp
Biotechnology · contribution
+0.063 pp
Company participation
25%
of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Dec 2021 · sorted by absolute contribution to 12-month change

CompanyCountryMarket capUniverse weight3M contribution12M contribution12M price returnAbove 6M weight average
Moderna →
MRNA
United States$103.0bn0.330%-0.216 pp+0.330 pp+143.1%No
Amgen →
AMGN
United States$126.7bn0.406%-0.018 pp-0.136 pp+0.9%No
Vertex Pharmaceuticals →
VRTX
United States$55.8bn0.179%+0.014 pp-0.070 pp-7.1%Yes
Biogen →
BIIB
United States$35.2bn0.113%-0.035 pp-0.040 pp-2.0%No
Incyte →
INCY
United States$16.2bn0.052%-0.001 pp-0.025 pp-15.6%No
Regeneron Pharmaceuticals →
REGN
United States$59.3bn0.190%-0.010 pp+0.006 pp+30.7%No
Gilead Sciences →
GILD
United States$91.1bn0.292%-0.016 pp-0.004 pp+30.0%No
AbbVie →
ABBV
United States$239.4bn0.767%+0.098 pp+0.001 pp+32.4%Yes

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.