Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine
Historical observation
20182026
Universe›Health Care›Biotechnology›Biotechnology
Biotechnology · weight
1.79%
Industry change · 12M
-0.61 pp
Biotechnology · contribution
-0.608 pp
Company participation
25%
of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Dec 2024 · sorted by absolute contribution to 12-month change

CompanyCountryMarket capUniverse weight3M contribution12M contribution12M price returnAbove 6M weight average
Amgen →
AMGN
United States$140.1bn0.318%-0.085 pp-0.142 pp-6.8%No
AbbVie →
ABBV
United States$314.0bn0.712%-0.100 pp-0.104 pp+18.9%No
Regeneron Pharmaceuticals →
REGN
United States$66.9bn0.152%-0.078 pp-0.094 pp-18.9%No
Vertex Pharmaceuticals →
VRTX
United States$103.7bn0.235%-0.044 pp-0.078 pp-1.0%No
Moderna →
MRNA
United States$16.0bn0.036%-0.024 pp-0.077 pp-58.2%No
Biogen →
BIIB
United States$22.3bn0.051%-0.015 pp-0.061 pp-40.9%No
Gilead Sciences →
GILD
United States$115.1bn0.261%+0.018 pp-0.040 pp+18.7%Yes
Incyte →
INCY
United States$13.3bn0.030%+0.001 pp-0.012 pp+10.0%Yes

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.