Observatory · observe first
Follow the allocation change
Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.
Historical time machine
Historical observation
20182026
1 · Sector
Weight and 12M allocation change
2 · Industry
Inside Health Care
Managed Health Care0.70%-0.62 ppHealth Care Equipment2.38%+0.59 ppLife Sciences Tools & Services0.93%-0.14 ppBiotechnology1.78%+0.14 ppPharmaceuticals3.35%+0.13 ppHealth Care Distributors0.40%+0.11 ppHealth Care Services0.42%+0.03 ppHealth Care Supplies0.09%-0.02 ppHealth Care Facilities0.18%+0.01 ppHealth Care Technology0.03%+0.01 pp
3 · Sub-industry
Inside Biotechnology
Biotechnology · weight
1.78%
Industry change · 12M
+0.14 pp
Biotechnology · contribution
+0.136 pp
Company participation
13%
of industry constituents above their 6M weight average
4 · Companies driving this sub-industry
Jul 2025 · sorted by absolute contribution to 12-month change
| Company | Country | Market cap | Universe weight | 3M contribution | 12M contribution | 12M price return | Above 6M weight average |
|---|---|---|---|---|---|---|---|
| Gilead Sciences → GILD | United States | $139.7bn | 0.295% | -0.024 pp | +0.125 pp | +52.4% | No |
| AbbVie → ABBV | United States | $333.9bn | 0.704% | -0.123 pp | +0.118 pp | +5.6% | No |
| Regeneron Pharmaceuticals → REGN | United States | $51.2bn | 0.108% | -0.027 pp | -0.074 pp | -49.3% | No |
| Moderna → MRNA | United States | $11.4bn | 0.024% | -0.002 pp | -0.058 pp | -75.2% | No |
| Vertex Pharmaceuticals → VRTX | United States | $117.3bn | 0.247% | -0.067 pp | +0.018 pp | -7.8% | No |
| Biogen → BIIB | United States | $18.8bn | 0.040% | -0.003 pp | -0.016 pp | -40.0% | No |
| Amgen → AMGN | United States | $158.7bn | 0.335% | -0.041 pp | +0.015 pp | -8.4% | No |
| Incyte → INCY | United States | $14.6bn | 0.031% | +0.002 pp | +0.008 pp | +15.1% | Yes |
Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.