Observatory · observe first
Follow the allocation change
Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.
Historical time machine
Historical observation
20182026
1 · Sector
Weight and 12M allocation change
2 · Industry
Inside Health Care
Pharmaceuticals3.42%-1.35 ppManaged Health Care0.84%-1.00 ppLife Sciences Tools & Services0.96%-0.47 ppBiotechnology1.80%-0.46 ppHealth Care Equipment2.41%-0.19 ppHealth Care Services0.47%-0.07 ppHealth Care Supplies0.09%-0.06 ppHealth Care Facilities0.20%-0.05 ppHealth Care Distributors0.39%+0.01 ppHealth Care Technology0.03%-0.00 pp
3 · Sub-industry
Inside Biotechnology
Biotechnology · weight
1.80%
Industry change · 12M
-0.46 pp
Biotechnology · contribution
-0.465 pp
Company participation
13%
of industry constituents above their 6M weight average
4 · Companies driving this sub-industry
Aug 2025 · sorted by absolute contribution to 12-month change
| Company | Country | Market cap | Universe weight | 3M contribution | 12M contribution | 12M price return | Above 6M weight average |
|---|---|---|---|---|---|---|---|
| Regeneron Pharmaceuticals → REGN | United States | $54.6bn | 0.113% | +0.009 pp | -0.156 pp | -50.8% | No |
| Amgen → AMGN | United States | $154.9bn | 0.321% | -0.030 pp | -0.112 pp | -10.9% | No |
| Vertex Pharmaceuticals → VRTX | United States | $100.3bn | 0.208% | -0.049 pp | -0.101 pp | -21.1% | No |
| AbbVie → ABBV | United States | $371.7bn | 0.771% | +0.026 pp | -0.067 pp | +11.0% | No |
| Gilead Sciences → GILD | United States | $140.2bn | 0.291% | -0.020 pp | +0.053 pp | +47.6% | No |
| Moderna → MRNA | United States | $9.4bn | 0.019% | -0.004 pp | -0.052 pp | -68.9% | No |
| Biogen → BIIB | United States | $19.4bn | 0.040% | -0.003 pp | -0.032 pp | -35.4% | No |
| Incyte → INCY | United States | $16.5bn | 0.034% | +0.006 pp | +0.004 pp | +28.9% | Yes |
Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.