Biotechnology
Biotechnology is losing market weight. Gained weight for 2 consecutive months.
Most of this industry's losses came from a few companies.
Where did the weight change come from?
12-month contribution in universe percentage points · contributions add to the industry change
The three largest same-direction contributors explain 71% of gross losses. Opposing contributions can make an individual company’s change larger than the industry’s net change.
How has it moved through history?
Share of matched S&P 500 members
Sep 2020 – Aug 2025 · market weight (%)
Relative performance
Industry return versus ACWI · no future data shown
Is participation broad or concentrated?
Actual constituent counts at this date, not the legacy synthetic breadth proxy
This is size concentration, not contribution to the 12-month change. The attribution above measures the latter.
Evidence can disagree
Independent dimensions · no combined score or bullish/bearish verdict
Other evidence and availability
Valuation data: unavailable; shown as zero placeholder.
Attention data: unavailable; shown as zero placeholder.
Actual fund flows: unavailable. No ETF, mutual-fund or institutional flow feed is connected.
Volume / turnover: unavailable in this dataset.
Follow the contribution to individual companies
Sorted by absolute 12-month weight contribution, not investment merit
| Company | Sub-industry | Country | Universe weight | 12M contribution | 12M price return | Revisions |
|---|---|---|---|---|---|---|
| Regeneron Pharmaceuticals → REGN | Biotechnology | United States | 0.113% | -0.156 pp | -50.8% | 0.0 |
| Amgen → AMGN | Biotechnology | United States | 0.321% | -0.112 pp | -10.9% | 0.0 |
| Vertex Pharmaceuticals → VRTX | Biotechnology | United States | 0.208% | -0.101 pp | -21.1% | 0.0 |
| AbbVie → ABBV | Biotechnology | United States | 0.771% | -0.067 pp | +11.0% | 0.0 |
| Gilead Sciences → GILD | Biotechnology | United States | 0.291% | +0.053 pp | +47.6% | 0.0 |
| Moderna → MRNA | Biotechnology | United States | 0.019% | -0.052 pp | -68.9% | 0.0 |
| Biogen → BIIB | Biotechnology | United States | 0.040% | -0.032 pp | -35.4% | 0.0 |
| Incyte → INCY | Biotechnology | United States | 0.034% | +0.004 pp | +28.9% | 0.0 |
Underlying monthly industry observations
| Month | Weight | 1M change | 3M change | 6M change | 12M change | Relative return · 12M |
|---|---|---|---|---|---|---|
| Aug 2025 | 1.797% | +0.014 pp | -0.066 pp | -0.244 pp | -0.465 pp | -18.1% |
| Jul 2025 | 1.783% | +0.011 pp | -0.285 pp | -0.067 pp | +0.136 pp | -18.5% |
| Jun 2025 | 1.772% | -0.091 pp | -0.373 pp | -0.023 pp | +0.144 pp | -16.4% |
| May 2025 | 1.863% | -0.206 pp | -0.178 pp | +0.018 pp | +0.259 pp | -11.1% |
| Apr 2025 | 2.068% | -0.077 pp | +0.218 pp | -0.059 pp | -0.207 pp | +0.5% |
| Mar 2025 | 2.145% | +0.105 pp | +0.350 pp | +0.023 pp | -0.208 pp | +1.7% |
| Feb 2025 | 2.041% | +0.190 pp | +0.196 pp | -0.221 pp | -0.329 pp | -1.7% |
| Jan 2025 | 1.850% | +0.055 pp | -0.277 pp | +0.203 pp | -0.658 pp | -16.4% |
| Dec 2024 | 1.795% | -0.050 pp | -0.328 pp | +0.167 pp | -0.608 pp | -14.3% |
| Nov 2024 | 1.845% | -0.282 pp | -0.417 pp | +0.242 pp | -0.449 pp | -8.0% |
| Oct 2024 | 2.127% | +0.004 pp | +0.480 pp | -0.148 pp | -0.341 pp | -3.6% |
| Sep 2024 | 2.123% | -0.139 pp | +0.494 pp | -0.231 pp | -0.405 pp | -6.3% |
| Aug 2024 | 2.262% | +0.615 pp | +0.658 pp | -0.108 pp | -0.146 pp | +2.8% |
| Jul 2024 | 1.647% | +0.019 pp | -0.628 pp | -0.861 pp | +0.028 pp | +8.5% |
| Jun 2024 | 1.628% | +0.025 pp | -0.725 pp | -0.774 pp | -0.019 pp | +4.6% |
| May 2024 | 1.603% | -0.672 pp | -0.766 pp | -0.690 pp | -0.163 pp | -2.9% |
| Apr 2024 | 2.275% | -0.078 pp | -0.233 pp | -0.193 pp | -0.335 pp | -10.9% |
| Mar 2024 | 2.353% | -0.016 pp | -0.049 pp | -0.174 pp | -0.336 pp | -10.5% |
| Feb 2024 | 2.369% | -0.139 pp | +0.076 pp | -0.039 pp | -0.275 pp | -8.6% |
| Jan 2024 | 2.508% | +0.106 pp | +0.040 pp | +0.890 pp | -0.174 pp | -3.2% |
| Dec 2023 | 2.402% | +0.109 pp | -0.125 pp | +0.756 pp | -0.493 pp | -15.8% |
| Nov 2023 | 2.294% | -0.175 pp | -0.114 pp | +0.527 pp | -0.520 pp | -18.2% |
| Oct 2023 | 2.468% | -0.059 pp | +0.850 pp | -0.142 pp | -0.259 pp | -12.4% |
| Sep 2023 | 2.527% | +0.119 pp | +0.881 pp | -0.163 pp | -0.121 pp | -4.5% |
| Aug 2023 | 2.408% | +0.789 pp | +0.641 pp | -0.237 pp | +0.016 pp | +1.6% |
| Jul 2023 | 1.619% | -0.028 pp | -0.992 pp | -1.064 pp | -0.790 pp | -3.2% |
| Jun 2023 | 1.647% | -0.120 pp | -1.043 pp | -1.248 pp | -1.112 pp | -11.3% |
| May 2023 | 1.766% | -0.844 pp | -0.878 pp | -1.047 pp | -0.805 pp | +1.8% |
| Apr 2023 | 2.610% | -0.079 pp | -0.072 pp | -0.116 pp | +0.110 pp | +11.9% |
| Mar 2023 | 2.690% | +0.045 pp | -0.205 pp | +0.041 pp | +0.179 pp | +17.8% |
| Feb 2023 | 2.645% | -0.038 pp | -0.169 pp | +0.252 pp | +0.258 pp | +23.6% |
| Jan 2023 | 2.683% | -0.212 pp | -0.044 pp | +0.274 pp | +0.351 pp | +27.8% |
| Dec 2022 | 2.895% | +0.081 pp | +0.246 pp | +0.137 pp | +0.567 pp | +40.6% |
| Nov 2022 | 2.814% | +0.087 pp | +0.421 pp | +0.243 pp | +0.442 pp | +38.1% |
| Oct 2022 | 2.727% | +0.078 pp | +0.319 pp | +0.227 pp | +0.379 pp | +41.8% |
| Sep 2022 | 2.649% | +0.256 pp | -0.110 pp | +0.138 pp | +0.136 pp | +23.3% |
| Aug 2022 | 2.392% | -0.016 pp | -0.179 pp | +0.006 pp | -0.174 pp | +7.9% |
| Jul 2022 | 2.408% | -0.350 pp | -0.092 pp | +0.076 pp | -0.142 pp | +9.2% |
| Jun 2022 | 2.758% | +0.187 pp | +0.248 pp | +0.430 pp | +0.638 pp | +17.6% |
| May 2022 | 2.571% | +0.071 pp | +0.185 pp | +0.199 pp | +0.495 pp | +11.4% |
| Apr 2022 | 2.500% | -0.010 pp | +0.168 pp | +0.152 pp | +0.416 pp | +7.5% |
| Mar 2022 | 2.511% | +0.124 pp | +0.183 pp | -0.002 pp | +1.383 pp | +1.5% |
| Feb 2022 | 2.386% | +0.054 pp | +0.014 pp | -0.180 pp | +1.280 pp | -3.3% |
| Jan 2022 | 2.332% | +0.004 pp | -0.016 pp | -0.219 pp | +0.958 pp | -10.9% |
| Dec 2021 | 2.328% | -0.044 pp | -0.184 pp | +0.208 pp | +0.063 pp | -8.3% |
| Nov 2021 | 2.372% | +0.024 pp | -0.194 pp | +0.296 pp | +0.023 pp | -11.0% |
| Oct 2021 | 2.348% | -0.164 pp | -0.203 pp | +0.264 pp | -0.078 pp | -16.0% |
| Sep 2021 | 2.512% | -0.054 pp | +0.392 pp | +1.384 pp | +2.510 pp | -17.0% |
| Aug 2021 | 2.566% | +0.016 pp | +0.490 pp | +1.460 pp | +2.563 pp | -16.2% |
| Jul 2021 | 2.550% | +0.430 pp | +0.466 pp | +1.176 pp | +2.548 pp | -21.1% |
| Jun 2021 | 2.121% | +0.045 pp | +0.993 pp | -0.144 pp | +2.117 pp | -26.3% |
| May 2021 | 2.076% | -0.008 pp | +0.969 pp | -0.273 pp | +2.073 pp | -29.3% |
| Apr 2021 | 2.084% | +0.956 pp | +0.710 pp | -0.342 pp | -1.011 pp | -29.6% |
| Mar 2021 | 1.128% | +0.021 pp | -1.137 pp | +1.125 pp | +1.125 pp | -26.4% |
| Feb 2021 | 1.107% | -0.267 pp | -1.242 pp | +1.104 pp | +1.105 pp | -15.6% |
| Jan 2021 | 1.374% | -0.891 pp | -1.052 pp | +1.371 pp | -1.006 pp | +0.9% |
| Dec 2020 | 2.265% | -0.084 pp | +2.262 pp | +2.262 pp | -0.288 pp | -7.7% |
| Nov 2020 | 2.349% | -0.077 pp | +2.346 pp | +2.346 pp | -0.272 pp | -7.7% |
| Oct 2020 | 2.426% | +2.423 pp | +2.423 pp | -0.669 pp | -0.055 pp | +2.1% |
| Sep 2020 | 0.003% | -0.000 pp | -0.000 pp | +0.000 pp | -2.317 pp | +18.0% |
How are these descriptive states defined?
Gaining / losing: 12-month weight change above +0.005pp / below −0.005pp. Direction and speed are separate dimensions, not mutually exclusive recommendations.
Accelerating / slowing: compare the most recent 3M change with the preceding 3M change. Accelerating means a positive change speeds up by >0.02pp. Slowing means the magnitude of movement declines by >0.02pp. A falling industry can also slow.
Reversing: the last two 3M changes have opposite signs, outside a ±0.005pp tolerance. Persistence counts consecutive same-direction monthly changes.
Broad / concentrated: company attribution, not a market-cap concentration shortcut. Concentrated means the three largest same-direction contributors account for ≥70% of gross same-direction changes; otherwise broad requires ≥60% of constituents moving with the industry. Other cases are mixed.
Weights use matched S&P 500 members’ market-cap estimates, based on SEC-reported shares available by each month-end and monthly closing prices. Companies without a matched price or share record are omitted, so the denominator is the matched sample rather than every index member. These are not official float-adjusted S&P weights. Flow is not measured.