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Observatory · observe first

Biotechnology

Biotechnology is losing market weight. Lost weight for 4 consecutive months.

Historical time machine
Historical observation
20182026
Reversing downwardConcentrated

Most of this industry's losses came from a few companies.

Universe weight
2.40%
$0.45T
12-month change
-0.71 pp
6-month change
+0.63 pp
3-month change
-0.30 pp
Company participation
57%
above their 6M weight average

Where did the weight change come from?

12-month contribution in universe percentage points · contributions add to the industry change

Sub-industries
Company attribution
AbbVie →-0.312 pp
All other companies-0.394 pp
Industry total-0.706 pp

The three largest same-direction contributors explain 80% of gross losses. Opposing contributions can make an individual company’s change larger than the industry’s net change.

How has it moved through history?

Share of matched S&P 500 members

Jan 2018 – Jun 2019 · market weight (%)

1.72.53.420182019

Relative performance

Industry return versus ACWI · no future data shown

849410420182019

Is participation broad or concentrated?

Actual constituent counts at this date, not the legacy synthetic breadth proxy

Above their 3M universe-weight average43%
Above their 6M universe-weight average57%
Above their 12M universe-weight average86%
Top 5 share of current industry market cap89.3%

This is size concentration, not contribution to the 12-month change. The attribution above measures the latter.

Evidence can disagree

Independent dimensions · no combined score or bullish/bearish verdict

Allocation · 12M-0.71 pp
Relative strength · 12M-11.3%
Price index return · 12M-6.0%
Earnings revisions · unavailable0.0
Allocation lost weight while relative performance fell. At least half of constituents are above their 6M weight average. These observations need not agree.
Other evidence and availability

Valuation data: unavailable; shown as zero placeholder.

Attention data: unavailable; shown as zero placeholder.

Actual fund flows: unavailable. No ETF, mutual-fund or institutional flow feed is connected.

Volume / turnover: unavailable in this dataset.

Follow the contribution to individual companies

Sorted by absolute 12-month weight contribution, not investment merit

CompanySub-industryCountryUniverse weight12M contribution12M price returnRevisions
AbbVie →
ABBV
BiotechnologyUnited States0.580%-0.312 pp-17.8%0.0
Amgen →
AMGN
BiotechnologyUnited States0.606%-0.135 pp+2.9%0.0
Biogen →
BIIB
BiotechnologyUnited States0.244%-0.127 pp-19.4%0.0
Gilead Sciences →
GILD
BiotechnologyUnited States0.463%-0.096 pp-1.2%0.0
Regeneron Pharmaceuticals →
REGN
BiotechnologyUnited States0.159%-0.038 pp-9.3%0.0
Incyte →
INCY
BiotechnologyUnited States0.098%+0.012 pp+26.8%0.0
Vertex Pharmaceuticals →
VRTX
BiotechnologyUnited States0.253%-0.010 pp+7.9%0.0
Underlying monthly industry observations
MonthWeight1M change3M change6M change12M changeRelative return · 12M
Jun 20192.403%-0.069 pp-0.300 pp+0.632 pp-0.706 pp-11.3%
May 20192.472%-0.024 pp-0.367 pp+0.715 pp-0.607 pp-8.7%
Apr 20192.496%-0.207 pp+0.834 pp+0.871 pp-0.587 pp-9.2%
Mar 20192.703%-0.136 pp+0.933 pp+0.949 pp-0.495 pp-3.7%
Feb 20192.839%+1.177 pp+1.081 pp+1.080 pp-0.582 pp-5.6%
Jan 20191.663%-0.108 pp+0.037 pp-1.462 pp-1.719 pp-1.0%
Dec 20181.771%+0.013 pp+0.016 pp-1.339 pp-1.611 pp+4.8%
Nov 20181.758%+0.133 pp-0.002 pp-1.321 pp-1.624 pp+3.7%
Oct 20181.625%-0.129 pp-1.499 pp-1.459 pp-1.757 pp-4.9%
Sep 20181.754%-0.005 pp-1.355 pp-1.444 pp-1.628 pp+0.4%
Aug 20181.759%-1.365 pp-1.320 pp-1.662 pp-1.623 pp-0.1%
Jul 20183.124%+0.015 pp+0.040 pp-0.258 pp-0.258 pp-2.6%
Jun 20183.109%+0.030 pp-0.089 pp-0.273 pp-0.273 pp-5.3%
May 20183.079%-0.005 pp-0.342 pp-0.303 pp-0.303 pp-6.9%
Apr 20183.084%-0.114 pp-0.298 pp-0.298 pp-0.298 pp-7.8%
Mar 20183.198%-0.224 pp-0.184 pp-0.184 pp-0.184 pp-6.1%
Feb 20183.421%+0.039 pp+0.039 pp+0.039 pp+0.039 pp+1.2%
Jan 20183.382%+0.000 pp+0.000 pp+0.000 pp+0.000 pp+0.0%
How are these descriptive states defined?

Gaining / losing: 12-month weight change above +0.005pp / below −0.005pp. Direction and speed are separate dimensions, not mutually exclusive recommendations.

Accelerating / slowing: compare the most recent 3M change with the preceding 3M change. Accelerating means a positive change speeds up by >0.02pp. Slowing means the magnitude of movement declines by >0.02pp. A falling industry can also slow.

Reversing: the last two 3M changes have opposite signs, outside a ±0.005pp tolerance. Persistence counts consecutive same-direction monthly changes.

Broad / concentrated: company attribution, not a market-cap concentration shortcut. Concentrated means the three largest same-direction contributors account for ≥70% of gross same-direction changes; otherwise broad requires ≥60% of constituents moving with the industry. Other cases are mixed.

Weights use matched S&P 500 members’ market-cap estimates, based on SEC-reported shares available by each month-end and monthly closing prices. Companies without a matched price or share record are omitted, so the denominator is the matched sample rather than every index member. These are not official float-adjusted S&P weights. Flow is not measured.