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Observatory · observe first

Biotechnology

Biotechnology is losing market weight. Lost weight for 2 consecutive months.

Historical time machine
Historical observation
20182026
Declining fasterBroad

The loss is shared across much of the industry.

Universe weight
3.08%
$0.50T
12-month change
-0.30 pp
6-month change
-0.30 pp
3-month change
-0.30 pp
Company participation
0%
above their 6M weight average

Where did the weight change come from?

12-month contribution in universe percentage points · contributions add to the industry change

Sub-industries
Company attribution
AbbVie →-0.080 pp
All other companies-0.219 pp
Industry total-0.298 pp

The three largest same-direction contributors explain 69% of gross losses. Opposing contributions can make an individual company’s change larger than the industry’s net change.

How has it moved through history?

Share of matched S&P 500 members

Jan 2018 – Apr 2018 · market weight (%)

3.13.33.42018

Relative performance

Industry return versus ACWI · no future data shown

93971012018

Is participation broad or concentrated?

Actual constituent counts at this date, not the legacy synthetic breadth proxy

Above their 3M universe-weight average0%
Above their 6M universe-weight average0%
Above their 12M universe-weight average0%
Top 5 share of current industry market cap91.7%

This is size concentration, not contribution to the 12-month change. The attribution above measures the latter.

Evidence can disagree

Independent dimensions · no combined score or bullish/bearish verdict

Allocation · 12M-0.30 pp
Relative strength · 12M-7.8%
Price index return · 12M-12.9%
Earnings revisions · unavailable0.0
Allocation lost weight while relative performance fell. Fewer than half of constituents are above their 6M weight average. These observations need not agree.
Other evidence and availability

Valuation data: unavailable; shown as zero placeholder.

Attention data: unavailable; shown as zero placeholder.

Actual fund flows: unavailable. No ETF, mutual-fund or institutional flow feed is connected.

Volume / turnover: unavailable in this dataset.

Follow the contribution to individual companies

Sorted by absolute 12-month weight contribution, not investment merit

CompanySub-industryCountryUniverse weight12M contribution12M price returnRevisions
AbbVie →
ABBV
BiotechnologyUnited States0.942%-0.080 pp-13.1%0.0
Biogen →
BIIB
BiotechnologyUnited States0.355%-0.065 pp-21.3%0.0
Amgen →
AMGN
BiotechnologyUnited States0.709%-0.061 pp-5.5%0.0
Gilead Sciences →
GILD
BiotechnologyUnited States0.581%-0.043 pp-13.2%0.0
Incyte →
INCY
BiotechnologyUnited States0.081%-0.028 pp-31.4%0.0
Regeneron Pharmaceuticals →
REGN
BiotechnologyUnited States0.175%-0.021 pp-17.2%0.0
Vertex Pharmaceuticals →
VRTX
BiotechnologyUnited States0.240%-0.001 pp-8.2%0.0
Underlying monthly industry observations
MonthWeight1M change3M change6M change12M changeRelative return · 12M
Apr 20183.084%-0.114 pp-0.298 pp-0.298 pp-0.298 pp-7.8%
Mar 20183.198%-0.224 pp-0.184 pp-0.184 pp-0.184 pp-6.1%
Feb 20183.421%+0.039 pp+0.039 pp+0.039 pp+0.039 pp+1.2%
Jan 20183.382%+0.000 pp+0.000 pp+0.000 pp+0.000 pp+0.0%
How are these descriptive states defined?

Gaining / losing: 12-month weight change above +0.005pp / below −0.005pp. Direction and speed are separate dimensions, not mutually exclusive recommendations.

Accelerating / slowing: compare the most recent 3M change with the preceding 3M change. Accelerating means a positive change speeds up by >0.02pp. Slowing means the magnitude of movement declines by >0.02pp. A falling industry can also slow.

Reversing: the last two 3M changes have opposite signs, outside a ±0.005pp tolerance. Persistence counts consecutive same-direction monthly changes.

Broad / concentrated: company attribution, not a market-cap concentration shortcut. Concentrated means the three largest same-direction contributors account for ≥70% of gross same-direction changes; otherwise broad requires ≥60% of constituents moving with the industry. Other cases are mixed.

Weights use matched S&P 500 members’ market-cap estimates, based on SEC-reported shares available by each month-end and monthly closing prices. Companies without a matched price or share record are omitted, so the denominator is the matched sample rather than every index member. These are not official float-adjusted S&P weights. Flow is not measured.