Observatory · observe first

Follow the allocation change

Matched S&P 500 members → sector → industry → sub-industry → company. Each step uses the same percentage points.

Historical time machine

Historical observation

20182026

Universe›Health Care›Biotechnology›Biotechnology

1 · Sector

Weight and 12M allocation change

Information Technology17.0%+0.98 pp Energy5.1%+0.38 pp Utilities3.4%+0.28 pp Real Estate3.4%+0.12 pp Health Care16.8%+0.09 pp Consumer Discretionary7.1%+0.05 pp Materials2.1%-0.04 pp Communication Services3.3%-0.22 pp Financials18.2%-0.27 pp Industrials15.0%-0.59 pp Consumer Staples8.6%-0.79 pp

2 · Industry

Inside Health Care

Biotechnology3.08%-0.30 pp Health Care Equipment2.98%+0.15 pp Managed Health Care2.08%+0.13 pp Pharmaceuticals5.60%+0.10 pp Life Sciences Tools & Services1.54%+0.03 pp Health Care Services0.68%-0.02 pp Health Care Distributors0.50%-0.01 pp Health Care Supplies0.14%+0.00 pp Health Care Facilities0.21%+0.00 pp Health Care Technology0.00%+0.00 pp

3 · Sub-industry

Inside Biotechnology

Biotechnology3.08%-0.298 pp

Broad

The loss is shared across much of the industry.

View all contributions →

Biotechnology · weight

3.08%

Industry change · 12M

-0.30 pp

Biotechnology · contribution

-0.298 pp

Company participation

of industry constituents above their 6M weight average

4 · Companies driving this sub-industry

Apr 2018 · sorted by absolute contribution to 12-month change

Company	Country	Market cap	Universe weight	3M contribution	12M contribution	12M price return	Above 6M weight average
AbbVie → ABBV	United States	$153.3bn	0.942%	-0.080 pp	-0.080 pp	-13.1%	No
Biogen → BIIB	United States	$57.7bn	0.355%	-0.065 pp	-0.065 pp	-21.3%	No
Amgen → AMGN	United States	$115.5bn	0.709%	-0.061 pp	-0.061 pp	-5.5%	No
Gilead Sciences → GILD	United States	$94.6bn	0.581%	-0.043 pp	-0.043 pp	-13.2%	No
Incyte → INCY	United States	$13.1bn	0.081%	-0.028 pp	-0.028 pp	-31.4%	No
Regeneron Pharmaceuticals → REGN	United States	$28.5bn	0.175%	-0.021 pp	-0.021 pp	-17.2%	No
Vertex Pharmaceuticals → VRTX	United States	$39.0bn	0.240%	-0.001 pp	-0.001 pp	-8.2%	No

Company contributions use weights among matched S&P 500 members and add through each level without rescaling. Companies without matched shares and prices are omitted. These observations do not establish official index weights or actual fund flows.